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What is the Chelerythrine Chloride ?
Chelerythrine Chloride is , while it's Molecular Formula is C21H18NO4. Used in Pharmaceutical Industry:
Chelerythrine Chloride is used as a research compound for its various biological activities, particularly in the development of treatments for cancer. Its ability to induce apoptosis in cancer cells and inhibit specific protein interactions makes it a valuable tool in the study and potential treatment of various malignancies.
Used in Neuroscience Research:
As an efficient antagonist of G-protein-coupled CB1 receptors, Chelerythrine Chloride is used in neuroscience research to study the role of these receptors in various physiological processes and their potential as therapeutic targets for conditions such as pain, addiction, and mood disorders.
Used in Cell Signaling Studies:
Due to its role as an independent activator of MAPK pathways, Chelerythrine Chloride is utilized in cell signaling research to understand the complex interactions between various signaling molecules and their impact on cellular processes, including cell growth, differentiation, and apoptosis.
Used in Anti-Inflammatory and Antibacterial Applications:
Chelerythrine Chloride's anti-inflammatory and antibacterial properties make it a potential candidate for the development of new treatments for inflammatory conditions and bacterial infections. Its use in these applications is currently under investigation in various research settings.
What is the CAS number for Chelerythrine Chloride ?
The CAS number of Chelerythrine Chloride is 34316-15-9.
More information of Chelerythrine Chloride 34316-15-9 are:
|
Synonyms |
Chelerythrine(6CI);[1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-(9CI);Toddalin; |
|
CAS?Number |
34316-15-9 |
|
Molecular Formula |
C21H18NO4 |
|
Molecular Weight |
348.378 |
|
Density |
1.2985 (rough estimate) |
|
Melting Point |
195-205oC |
|
Boiling Point |
496.37°C (rough estimate) |
|
HS CODE |
2933990090 |
|
PSA |
40.80000 |
|
LogP |
0.72060 |
What is Chelerythrine Chloride (34316-15-9) used for?
Chelerythrine chloride is the chloride form of Chelerythrine chloride which is a benzophenanthridine alkaloid isolated from the plant Chelidonium majus (greater celandine). It is a kind of potent, selective, and cell-permeable protein kinase C inhibitor, an efficient antagonist of G-protein-coupled CB1 receptors, and an independent activator of MAPK pathways. It has a wide range of biological activities including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. It has reported of that it is capable of inducing apoptosis in HL-60 human promyelocytic leukemia cells and several other cancer cell lines. The underlying mechanism is through its effects of inhibiting the binding of BclXL to Bax or Bad.
InChI:InChI=1/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H,11H2,1-3H3/q+1
Articles related to Chelerythrine Chloride:
|
Article |
Source |
|
Dihydrochelerythrine and its derivatives: Synthesis and their application as potential G-quadruplex DNA stabilizing agents |
Malhotra, Rajesh,Rarhi, Chhanda,Diveshkumar,Barik, Rajib,D'Cunha, Ruhee,Dhar, Pranab,Kundu, Mrinalkanti,Chattopadhyay, Subrata,Roy, Subho,Basu, Sourav,Pradeepkumar,Hajra, Saumen , p. 2887 - 2896 (2016/06/13) |
How to get the best price on Chelerythrine Chloride?
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