Details
Manufacturer supply top purity 1-(bromomethyl)cyclohexene 37677-17-1 with ISO standards
- Molecular Formula: C7H11 Br
- Molecular Weight: 175.068
- Vapor Pressure: 1.97mmHg at 25°C
- Boiling Point: 170.3°Cat760mmHg
- Flash Point: 53.3°C
- PSA： 0.00000
- Density: 1.326g/cm3
- LogP: 2.88170
1-(bromomethyl)cyclohexene(Cas 37677-17-1) Usage
|
General Description |
1-(bromomethyl)cyclohexene is a chemical compound with the molecular formula C7H11Br. It is a brominated cyclohexene derivative that is used in organic synthesis and as an intermediate in the production of various compounds. The compound is a colorless liquid with a pungent odor, and it is classified as a hazardous substance due to its potential health and environmental hazards. 1-(bromomethyl)cyclohexene is primarily used in the pharmaceutical and agrochemical industries, where it serves as a building block for the synthesis of various compounds with biological activity. It is important to handle and use this chemical with caution, following proper safety protocols and guidelines to ensure the safety of personnel and the environment. |
InChI:InChI=1/C7H11Br/c8-6-7-4-2-1-3-5-7/h4H,1-3,5-6H2
37677-17-1 Relevant articles
Lithium Chloride Catalyzed Asymmetric Domino Aza-Michael Addition/[3 + 2] Cycloaddition Reactions for the Synthesis of Spiro- and Bicyclic α,β,γ-Triamino Acid Derivatives
Just, David,Hernandez-Guerra, Daniel,Kritsch, Susanne,Pohl, Radek,Císa?ová, Ivana,Jones, Peter G.,Mackman, Richard,Bahador, Gina,Jahn, Ullrich
, p. 5213 - 5221 (2018)
Angularly and peri-fused tricyclic pyrro...
Regiospecific Synthesis of Calcium-Independent Daptomycin Antibiotics using a Chemoenzymatic Method
Mupparapu, Nagaraju,Lin, Yu-Hsin Cindy,Kim, Tae Ho,Elshahawi, Sherif I.
supporting information, p. 4176 - 4182 (2021/02/01)
Daptomycin (DAP) is a calcium (Ca2+)-dep...
Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy)carbamates
Hazelden, Ian R.,Carmona, Rafaela C.,Langer, Thomas,Pringle, Paul G.,Bower, John F.
, p. 5124 - 5128 (2018/03/26)
Ligand-enabled aza-Heck cyclizations and...
Stereospecific Alkene Aziridination Using a Bifunctional Amino-Reagent: An Aza-Prilezhaev Reaction
Farndon, Joshua J.,Young, Tom A.,Bower, John F.
supporting information, p. 17846 - 17850 (2019/01/04)
In situ deprotection (TFA) of O-Ts activ...
37677-17-1 Process route
-
-
18448-47-0
methyl cyclohex-1-ene-1-carboxylate
-
-
37677-17-1
1-bromomethylcyclohexene
| Conditions | Yield |
|---|---|
|
methyl cyclohex-1-ene-1-carboxylate;
With
lithium aluminium tetrahydride;
Inert atmosphere;
With
phosphorus tribromide;
Inert atmosphere;
|
86%
|
|
With
lithium aluminium tetrahydride; phosphorus tribromide;
Yield given. Multistep reaction;
|
|
|
Multi-step reaction
with
2
steps
1: LiAlH4
2: CBr4
; PPh3
/ CH2
Cl2
With
lithium aluminium tetrahydride; carbon tetrabromide; triphenylphosphine;
In
dichloromethane;
|
|
|
Multi-step reaction
with
2
steps
1: DIBAL-H / CH2
Cl2
; hexane / -78 °C
2: CBr4
; PPh3
/ CH2
Cl2
/ 20 °C
With
carbon tetrabromide; diisobutylaluminium hydride; triphenylphosphine;
In
hexane; dichloromethane;
|
|
|
Multi-step reaction
with
2
steps
1: DIBAL-H / CH2
Cl2
; hexane / 2.5 h / -78 °C
2: CBr4
; PPh3
/ CH2
Cl2
/ 3 h / 20 °C
With
carbon tetrabromide; diisobutylaluminium hydride; triphenylphosphine;
In
hexane; dichloromethane;
|
|
|
Multi-step reaction
with
2
steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C
2: phosphorus tribromide / diethyl ether / 16 h / 0 - 20 °C
With
lithium aluminium tetrahydride; phosphorus tribromide;
In
tetrahydrofuran; diethyl ether;
|
|
|
Multi-step reaction
with
2
steps
1: diisobutylaluminium hydride / dichloromethane; toluene / 1 h / -78 °C
2: phosphorus tribromide; pyridine / dichloromethane / 16 h / 0 - 20 °C
With
pyridine; phosphorus tribromide; diisobutylaluminium hydride;
In
dichloromethane; toluene;
|
|
|
Multi-step reaction
with
2
steps
1: lithium aluminium tetrahydride / diethyl ether / 0.5 h / 0 °C / Inert atmosphere
2: phosphorus tribromide / diethyl ether / 0 - 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; phosphorus tribromide;
In
diethyl ether;
|
|
|
Multi-step reaction
with
2
steps
1: diisobutylaluminium hydride / dichloromethane / 2 h / -78 °C
2: phosphorus tribromide / diethyl ether / 0 - 20 °C
With
phosphorus tribromide; diisobutylaluminium hydride;
In
diethyl ether; dichloromethane;
|
|
|
Multi-step reaction
with
2
steps
1: diisobutylaluminium hydride / dichloromethane / 2 h / -78 °C
2: phosphorus tribromide / diethyl ether / 18 h / 0 - 20 °C
With
phosphorus tribromide; diisobutylaluminium hydride;
In
diethyl ether; dichloromethane;
|
-
-
558-13-4
carbon tetrabromide
-
-
4845-04-9
1-cyclohexene-1-methanol
-
-
37677-17-1
1-bromomethylcyclohexene
| Conditions | Yield |
|---|---|
|
With
triphenylphosphine;
In
dichloromethane; pentane;
|
37677-17-1 Upstream products
-
4845-04-9
1-cyclohexene-1-methanol
-
22690-21-7
1-bromo-1-bromomethylcyclohexane
-
18448-47-0
methyl cyclohex-1-ene-1-carboxylate
-
1617-22-7
cyclohex-1-enecarboxylic acid ethyl ester
37677-17-1 Downstream products
-
104507-68-8
1-(1-cyclohexen-1-ylmethyl)-1-piperidine
-
13705-51-6
Dimethyl-2,2-(cyclohexen-1')yl-3-propionitril
-
57428-08-7
1-(2-Diethoxymethyl-allyl)-cyclohexene
-
50996-71-9
1-((E)-3-Isopropylsulfanyl-allyl)-2-methylene-cyclohexane
Related Products
-
4-NitrobenzaldoximeCAS：1129-37-9
-
-
isoaminileCAS：77-51-0
-
2-Ethyl-N,N-dimethylhexanamideCAS：81499-27-6